For laboratory research use only. Not for human, clinical, diagnostic, or therapeutic use.
Modified Semax Analog
Adamax
Synthetic heptapeptide derived from Semax (a modified ACTH(4-7) analog). Sequence Ac-MEHFPGP-AG-NH₂ with C-terminal adamantyl modification. C₄₄H₆₁N₁₁O₁₃S, MW ~984.1 g/mol. The acetyl and adamantyl modifications are intended to improve metabolic stability and membrane permeability relative to the unmodified parent peptide. Lyophilized powder for reconstitution.
Fill weight
10 mg
$79.00
● IN STOCK
Technical specifications
Compound data
MOLECULAR DATA
Structural profile
ClassSynthetic heptapeptide; modified Semax analog
SequenceAc-MEHFPGP-AG-NH₂ (with adamantyl modification at C-terminus)
Residues9
FormulaC₄₄H₆₁N₁₁O₁₃S
Mol. weight~984.1 g/mol
BIOLOGICAL ORIGIN
Parent molecule & position
Derived fromSemax (modified ACTH(4-7) analog)
Parent length7 residues
PositionN-terminal acetylation + C-terminal adamantyl modification
Reported in vitro activityBDNF expression modulation; neurotrophic / cognitive-pathway signaling
Receptor associationNot a direct receptor agonist; pathway-level effects via BDNF/TrkB signaling
HANDLING & STORAGE
Storage parameters
LYOPHILIZED
−20°C
Store sealed and protected from moisture. Stable at −20°C until reconstitution.
IN SOLVENT
2–8°C
Once reconstituted with bacteriostatic water, refrigerate. Use within 4 weeks.
LIGHT
SHIELD
Protect from direct light during storage and handling
Bibliographic references
Literature cited
NEUROSCIENCE LETTERS · 2006
Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
16996037
JOURNAL OF NEUROCHEMISTRY · 2006
Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain
16635254
JOURNAL OF MOLECULAR NEUROSCIENCE · 2009
Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina under Semax action
19662538
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES · 2021
Brain Protein Expression Profile Confirms the Protective Effect of the ACTH(4-7)PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia-Reperfusion
34201112
Research use notice
This product is sold for in-vitro laboratory research use only. It is not intended for use in humans, not intended for diagnostic use, and not intended for therapeutic applications. This product is not a drug, food, cosmetic, dietary supplement, or medical device, and has not been evaluated by the FDA for any use.
Any scientific literature referenced on this page is provided as bibliographic context for the compound's published research history. Citations do not constitute claims regarding the properties, effects, or applications of this product, and Biovexia LLC makes no representation regarding outcomes of any research conducted with this product.
Purchaser is responsible for compliance with all applicable federal, state, local, and institutional regulations governing the handling, storage, and use of research chemicals.
Any scientific literature referenced on this page is provided as bibliographic context for the compound's published research history. Citations do not constitute claims regarding the properties, effects, or applications of this product, and Biovexia LLC makes no representation regarding outcomes of any research conducted with this product.
Purchaser is responsible for compliance with all applicable federal, state, local, and institutional regulations governing the handling, storage, and use of research chemicals.
