For laboratory research use only. Not for human, clinical, diagnostic, or therapeutic use.
Multi-Receptor Agonist Peptide
BL-RT
Synonyms: LY3437943 · GLP-1 / GIP / GCGR tri-agonist
CAS: 2381089-83-2
CAS: 2381089-83-2
Synthetic peptide with reported agonist activity at multiple metabolic-related receptors. Lyophilized powder for reconstitution.
Fill weight
● IN STOCK
Technical specifications
Compound data
MOLECULAR DATA
Structural profile
ClassSynthetic triple-agonist peptide
Sequence39-residue engineered peptide (C20 diacid side chain)
Residues39
FormulaC₂₂₁H₃₄₂N₄₆O₆₈
Mol. weight4,731.33 g/mol
CAS2381089-83-2
PubChem Database → BIOLOGICAL ORIGIN
Parent molecule & position
Parent lengthN/A — synthetic engineered triagonist
PositionN/A — designed sequence (not derived from a single parent protein)
Jastreboff et al., NEJM 389(6):514–526, 2023 →
HANDLING & STORAGE
Storage parameters
LYOPHILIZED
−20°C
Store sealed and protected from moisture. Stable at −20°C until reconstitution.
IN SOLVENT
2 — 8°C
Once reconstituted with bacteriostatic water, refrigerate. Use within 4 weeks.
LIGHT
SHIELD
Protect from direct light during storage and handling.
Bibliographic references
Literature cited
CELL METABOLISM · 2022
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss
PMID: 35985340 · DOI: 10.1016/j.cmet.2022.07.013
THE LANCET · 2022
LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b trial
DOI: 10.1016/S0140-6736(22)02033-5
STAR PROTOCOLS · 2023
Differentiation of human subcutaneous adipocytes and measurement of lipolytic function induced by GIP or LY3437943
DOI: 10.1016/j.xpro.2023.102304
NATURE METABOLISM · 2023
Gut hormone co-agonists for the treatment of obesity: from bench to bedside
DOI: 10.1038/s42255-023-00812-z
Research use notice
This product is sold for in-vitro laboratory research use only. It is not intended for use in humans, not intended for diagnostic use, and not intended for therapeutic applications. This product is not a drug, food, cosmetic, dietary supplement, or medical device, and has not been evaluated by the FDA for any use.
Any scientific literature referenced on this page is provided as bibliographic context for the compound's published research history. Citations do not constitute claims regarding the properties, effects, or applications of this product, and Biovexia LLC makes no representation regarding outcomes of any research conducted with this product.
Purchaser is responsible for compliance with all applicable federal, state, local, and institutional regulations governing the handling, storage, and use of research chemicals.
Any scientific literature referenced on this page is provided as bibliographic context for the compound's published research history. Citations do not constitute claims regarding the properties, effects, or applications of this product, and Biovexia LLC makes no representation regarding outcomes of any research conducted with this product.
Purchaser is responsible for compliance with all applicable federal, state, local, and institutional regulations governing the handling, storage, and use of research chemicals.